Arthrys and the treatment of pain

Pain is a multifactorial pathology with social, psychological, and emotional components. In medicine, it is commonly considered as the consequence of a pathology or a trauma, but recently pain is acquiring relevance on its right and no longer only as a symptom. For instance, the pain that sometimes affects muscles, tendons, and joints depends on many factors, such as trauma, injuries, postural defects, and overload conditions. However, if appropriate, a doctor can specifically diagnose low back pain or knee pain. It is possible to diagnose osteoarthritis by observing articular cartilage degeneration on an x-ray, or tendon rupture on ultrasounds/MRI, but there is no absolute correlation between clinical signs and pain.

Pain leads patients to lose functions in daily, work, and sports activities, resulting in a challenge to clinicians. Except for orthopedic issues requiring surgery, musculoskeletal pain is often addressed with oral drugs or local cortisone infiltration, which are only temporary relief. However, to offer better benefits, pain therapy can take advantage of molecules and formulations with targeted action.

For joint pathologies, such as arthrosis, the use of hyaluronic acid (of different molecular weights) can provide relief to patients with joint pain through viscosupplementation, which improves the viscosity and elasticity of the synovial fluid.  Alternatively, regenerative medicine allows the use of the patient’s cells and elements to trigger the self-healing processes of injured tissues. One example is the use of Platelet-Rich Plasma (commonly known PRP, its acronym, or growth factors) that is obtained from blood withdraw from the patient himself and used immediately, after appropriate centrifugation.

Arthrys low molecular weight collagen peptides have a specific reinforcing action for connective tissue structures. Once injected into the site of interest, their concentration gradient can counteract the degradation phenomena affecting the extracellular matrix. Moreover, their weight of about 3kDa allows them to interact in the processes of inflammation and pain. The presence of Vitamin C and Magnesium protects the peptides from oxidation and allows a further antalgic action and the improvement of the cellular adhesion of the progenitor cells involved in the reparative processes.

Arthrys is a ready and easy-to-use solution that can quickly and naturally counteract pain and other symptoms of limited functionality.

The subjectivity of pain can have consequences on the response to therapy: awareness of the diagnosis and expectations of recovery are psychological features that may influence the clinical outcome. To find a solution to the high variability in response to treatments, research and development of new products are working to provide new and more effective solutions to combat pain.